What are NAD+ injections?

This guide sets out what NAD+ injections are, who offers them in the UK, how they are regulated and what research exists, using primary sources and our own dataset of 92 verified providers.

We do not provide, sell or arrange treatment, and nothing here is a recommendation.

What are NAD+ injections?

NAD+ injections are doses of NAD+ given by needle into a muscle (intramuscular, IM) or just under the skin (subcutaneous, SC), as distinct from a drip into a vein (intravenous, IV).

NAD+ itself is a coenzyme found in cells, and our guide to what NAD+ is explains the chemistry ¹.

In our dataset, 23 of the 92 verified UK providers list an injection route: 12 list injection only and 11 list both injection and IV ².

A further 67 list IV only and 2 do not state a route ².

“Verified” means we read each provider’s own page on 11 November 2026; the dataset is not a complete register of UK providers.

How are NAD+ injections given?

Clinics in our dataset describe injections as IM, SC, or “IM or SC” without choosing.

Of the 12 listings that offer injection only, 4 say IM, 6 say IM or SC and 2 do not say which ².

Across all 92 listings, 82 are fixed clinics, 4 are mobile only and 6 are both ².

We did not record who gives the injection at each clinic, so we cannot tell you from our data.

If an NAD+ product counts as a prescription-only medicine, UK law allows parenteral administration (by injection or infusion) only by an appropriate practitioner, or by someone acting on that practitioner’s directions ³.

The Human Medicines Regulations list the appropriate practitioners as a doctor, a dentist, a supplementary prescriber, a nurse independent prescriber and a pharmacist independent prescriber ³.

The Nursing and Midwifery Council says the legal method for prescribing, including when a prescriber delegates the administration, is a Patient Specific Direction ⁴.

Are NAD+ injections the same as NAD+ IV therapy?

No: both go in by needle rather than by mouth, but an injection is a needle dose into muscle or under the skin, while IV therapy runs through a cannula in a vein as a drip over a period of time.

The table compares what we recorded for each route; we never pool injection and IV prices, because the products and doses differ.

	Injection (IM or SC)	IV drip
Listed by (of 92 verified providers)	23 2	78 2
Dose labels in published prices	50 mg, 60 mg or 100 mg where a dose is named (5 of 10 price points) 2	250 mg or 500 mg for 29 of 36 price points 2
Single-session price, median, as displayed on clinic websites on 11 November 2026	£90 (n = 10 price points, 10 providers; range £50 to £150) 2	£300 (n = 36 price points, 22 providers; range £150 to £500) 2
Human outcomes trials found	None for IM 5; no human studies of SC found in our searches	None for ageing or wellness 5; one small pilot of NAD+ chemistry 6

Our guide to NAD+ IV therapy sets out the drip route in full.

Is NAD+ for injection a licensed medicine in the UK?

We could not confirm that any NAD+ injectable holds a UK marketing authorisation, and we found no public MHRA statement classifying NAD+ either way.

The MHRA’s products database did not return readable results to automated search, so licensing status is unverified rather than known; it is worth asking a clinic which product it uses and where it comes from.

Here is what the rules and regulators say, and where each statement comes from:

• Under the Human Medicines Regulations 2012, a medicinal product includes any substance presented as having properties of preventing or treating disease in human beings ⁷.
• An unauthorised medicinal product may not be sold or supplied, subject to exemptions such as “specials” ⁸.
• The MHRA says the specials exemption is narrow because those products may not have been assessed for safety, quality and efficacy, and that the “special need” is the individual patient’s clinical need, not cost or convenience ⁹.
• Medicinal products for parenteral administration are available only on prescription, if the product is a medicinal product ¹⁰.
• In a ruling of 22 April 2020 (A20-1059547) on Instagram posts about an NAD+ IV drip, the ASA wrote that it “understood that the IV drip offered by the advertiser was not licensed as a medicinal product” ¹¹.
• The Observer reported in February 2025 that an MHRA spokesperson said making medicinal claims about NAD+ breaches its regulations, and that the MHRA had taken action against seven clinics offering NAD+ for medicinal purposes ¹².

The ASA’s wording records its understanding in a ruling and is not an MHRA licensing decision.

We also searched the NHS website and NICE on 11 November 2026 and found no page on NAD+ and no NICE guidance ^13, 14.

Our guide to the UK legal status goes into the detail.

Who gives NAD+ injections in the UK?

In our dataset they are mostly fixed clinics in England, with 41 of the 92 verified providers (44.6 per cent) in London and 9 of the 23 injection listings there ².

The 92 providers are 89 in England, 2 in Wales and 1 listed UK-wide, and we verified none in Scotland or Northern Ireland ².

We matched each of the 92 against the Care Quality Commission (CQC) register’s open data, as at 2 November 2026 ¹⁵.

Forty-one matched a CQC-registered location (33 high-confidence matches and 8 medium), 5 matched a provider but not the clinic’s own address, 45 were not found and 1 in Wales could not be checked ¹⁵.

Of the 41 matches, 39 list “Treatment of disease, disorder or injury” among their registered activities, and the other 2 list only diagnostic and screening procedures ¹⁵.

Not every listed clinic is CQC-registered, and “not found” does not prove a clinic is unregistered.

Equally, CQC registration does not mean the NAD+ service itself is regulated: CQC found in 2018 that an IV and IM vitamin clinic’s wellbeing-only services were outside its scope of registration ¹⁶.

CQC’s guidance also says the “Treatment of disease, disorder or injury” activity does not include interventions carried out purely for cosmetic purposes ¹⁷.

In Wales, Healthcare Inspectorate Wales says services provided by health professionals who are not registered with the General Medical Council, for example nurses, do not usually need its registration unless a listed service is provided ¹⁸.

You can compare listed providers, with their route and any published price, in our directory of listed clinics.

What doses and schedules do UK clinics list?

Clinics publish dose labels that vary, and we report what the pages say, not what anyone should take.

This table shows the 10 single-session injection price points we recorded, as displayed on clinic websites on 11 November 2026 (10 providers).

Dose label on the page	Price points	Prices shown
60 mg	3	£60, £119, £120
50 mg	1	£80
100 mg	1	£125
No dose stated	5	£50, £65, £80, £100, £150

Across all 10 points the range is £50 to £150 and the median is £90 ².

Schedules are rarely stated in the price text we recorded: one listing prices a course of four injections, which we kept out of the single-session figures ².

We did not record schedules systematically, so treat that as an example, not a survey.

We found no human study that tested the dose or schedule of an NAD+ injection, so a dose on a clinic page is a clinic’s choice, not an evidence-based standard.

The full price breakdown is in our guide to the prices clinics publish.

What does the evidence say about NAD+ injections?

Very little: a 2026 systematic review found no outcomes trials of intravenous or intramuscular NAD+ for ageing or wellness ⁵.

Our PubMed searches on 11 November 2026 for subcutaneous NAD+ in humans returned no results.

The nearest evidence is for IV NAD+, which a 2026 narrative review says “remains preliminary and insufficient to support routine clinical or wellness use” ¹⁹.

One registered randomised trial (NCT06919328, recruiting, estimated enrolment 70, no results posted) compares injected nicotinamide riboside, injected NAD+ and placebo in healthy adults ²⁰.

The ASA’s expert advice is that it is “unlikely to be acceptable to rely on studies which examine regular supplementation and extrapolate it to a one-off IVNT infusion” ²¹.

Reported side effects come mainly from small IV studies, and our guide to side effects sets them out.

Our guide to what the evidence says about benefits looks at each claimed use in turn.

What are the alternatives, such as oral NMN or NR?

Oral NR and NMN are the most studied way of raising NAD+ measures in people, but they are different molecules and no published trial we found compares them with injected NAD+.

The 2026 systematic review found that oral NR and NMN consistently raised NAD-related measures and were generally well tolerated over weeks to months, while health-outcome effects were often null or endpoint-specific ⁵.

We found no published trial that compares injected NAD+ with oral NMN or NR for any health outcome, based on our searches and the two 2026 reviews ²².

The NHS says a varied diet supplies the niacin you need ²³.

Our guide to NMN and NR compared sets out the differences in detail.

How do I check a clinic before getting in touch?

Ask who prescribes and who administers, what the product is and where it comes from, and which regulator registers the clinic, then check the answer on the regulator’s own register.

Our guide on how to check a clinic goes through each step; these are the questions most worth asking:

• Who is the prescriber, what is their professional registration (GMC, NMC or GPhC), and have they assessed my medical history? The NMC says prescribers need enough knowledge of your health and your full medical and prescribing history ⁴.
• Is there a prescription or Patient Specific Direction for me, rather than a stock supply? ⁴
• Who will give the injection, and what is their registration? ³
• Is the clinic registered with CQC (England), Healthcare Inspectorate Wales or Healthcare Improvement Scotland, and which registered activities cover this service? Ask for the provider name and location ID.
• What is the product, who supplies it and is it a licensed medicine, an unlicensed “special” or an import? ⁹
• What human evidence do you rely on for the goal I have, and is it from trials of NAD+ injections specifically? ⁵
• What is known about long-term safety, and will you put in writing that it is not known? ¹⁹
• Can I take independent medical advice, for example from my GP, first? ²⁴

This page is general information, not medical advice. Speak to your GP or a registered prescriber before deciding anything about NAD+ injections, and read our medical disclaimer.

It was drafted with AI assistance from a fact-pack of primary sources by the NAD Injections editorial team and has not been clinically reviewed.